Chemoselective hydrogenation of nitroarenes and deoxygenation of pyridine N-oxides with H2 catalyzed by MoO2Cl2
نویسندگان
چکیده
Article history: Received 3 November 2008 Revised 2 December 2008 Accepted 9 December 2008 Available online 16 December 2008
منابع مشابه
Pd/C-catalyzed chemoselective hydrogenation in the presence of a phenolic MPM protective group using pyridine as a catalyst poison.
Employment of a Pd/C-pyridine combination as a catalyst is a very useful method for the selective removal (hydrogenolysis) of phenolic O-benzyl, N-Cbz and benzyl ester protective groups and for the selective hydrogenation of nitro and olefin functions of phenol derivatives protected with the MPM group. These discriminatory results are apparently attributable to the effect of pyridine. The MPM g...
متن کاملPorous vanadium-doped titania with active hydrogen: a renewable reductant for chemoselective hydrogenation of nitroarenes under ambient conditions.
A vanadium-doped porous titania rich in active hydrogen (V-TiO(2)(H*)) has been successfully prepared and demonstrated to be an efficient and green reductant with renewable capacity. This V-TiO(2)(H*) material can instantly (<10 s) and selectively reduce nitroarenes to aminoarenes under ambient conditions without catalysts.
متن کاملCopper-catalyzed oxygen atom transfer of N-oxides leading to a facile deoxygenation procedure applicable to both heterocyclic and amine N-oxides.
Deoxygenation of various types of N-oxides including both heterocyclic and alkyl(aryl)amine derivatives has successfully been developed by the copper-catalyzed oxygen atom transfer using diazo compounds as the oxygen acceptor. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance under mild conditions.
متن کاملMicrowave Assisted Rapid, Efficient and Chemoselective Deoxygenation of Sulfoxides to Thioethers Using Zn / AcOH on Silica Gel
Zn/AcOH on silica gel converts a range of structurally different sulfoxides to their corresponding thioethers in excellent yields under microwave irradiation. It has been found that chemoselective deoxygenation of sufoxides can be achieved in the presence of other reducible functional groups such as acetals, acids, amides, esters, ketones and nitriles.
متن کاملBase free transfer hydrogenation using a covalent triazine framework based catalyst
Transfer hydrogenation (TH) reaction – the addition of hydrogen to an unsaturated group of an organic molecule from a source other than H2 – has been gaining a lot of attention as it is an appealing alternative to direct hydrogenation. The reasoning behind it is the elimination of pressurised hydrogen and high pressure equipment use. Besides, a conventional hydrogenation catalyst is rarely sele...
متن کامل